12002-53-8

Liquid. Soluble in most organic solvents; insoluble in water.

As attractant in medfly traps.

Trimedlure is an attractant for successful fruit fly control.

Trimedlure is commercially synthesised through a stereoselective esterification process involving cyclohexane-based intermediates and chloromethylation, yielding a potent blend of isomers used as a pheromone. The production begins with the preparation of cyclohexene carboxylic acid derivatives, which are chloromethylated to introduce the key functional group responsible for insect attraction. This intermediate is then esterified with tert-butyl alcohol under acidic conditions, typically using sulphuric acid or a Lewis acid catalyst, to form the tert-butyl ester. The reaction is carefully controlled to favour the formation of the active stereoisomers, particularly the (1R,2S,5R) and (1R,2S,4R) configurations, which exhibit the highest biological activity

Non-toxic mode of action. Acts as an attractant

Semiochemical; Insecticide