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Withaphysalin E is a natural product that can be isolated from Physalis divericata. Withaphysalin E can be used in the study of non-small cell lung cancer[1][2].

[1] Rao PC, et al. Cytotoxicity of withasteroids: withametelin induces cell cycle arrest at G2/M phase and mitochondria-mediated apoptosis in non-small cell lung cancer A549 cells. Tumour Biol. 2016 Sep;37(9):12579-12587. DOI:10.1007/s13277-016-5128-5
[2] Ma L, et al. Withaphysanolide A, a novel C-27 norwithanolide skeleton, and other cytotoxic compounds from Physalis divericata. Tetrahedron letters, 2007, 48(3): 449-452