ChemicalBook CAS DataBase List 1185887-21-1

1185887-21-1

Name	AB-CHMINACA
CAS	1185887-21-1
Molecular Formula	C20H28N4O2
Molecular Weight	356.46
MOL File	1185887-21-1.mol

Chemical Properties

Boiling point	625.8±35.0 °C(Predicted)
density	1.27±0.1 g/cm3(Predicted)
solubility	DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 3 mg/ml
form	A neat solid
pka	11.37±0.46(Predicted)

Hazard Information

Description

AB-CHMINACA (CRM) (Item No. 27237) is a certified reference material categorized as a synthetic cannabinoid. It has been found in Spice-type herbal blends and is associated with slurred speech, confusion, lethargy, and lack of coordination in cases of driving under the influence. AB-CHMINACA is regulated as a Schedule I compound in the United States. AB-CHMINACA (CRM) (Item No. 27237) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Uses

AB-CHMINACA is an indazole-based synthetic cannabinoid (CB) that is structurally related to AB-FUBINACA, a high affinity ligand of the central CB1 receptor. Synthetic Cannabinoids

References

[1] BRIANNA L PETERSON Fiona J C. Concentrations of AB-CHMINACA and AB-PINACA and Driving Behavior in Suspected Impaired Driving Cases.[J]. Journal of analytical toxicology, 2015, 39 8: 642-647. DOI: 10.1093/jat/bkv091
[2] KHALED MASOUD MOHAMED MASOUD Alanoud M A Syed Mujeebuddin Syed. Analyte protectant approach to protect amide-based synthetic cannabinoids from degradation and esterification during GC–MS analysis[J]. Journal of Chromatography A, 2024, 1730: Article 465022. DOI: 10.1016/j.chroma.2024.465022
[3] SOHEIR ALI MOHAMMAD. Toxic effects of AB-CHMINACA on liver and kidney and detection of its blood level in adult male mice.[J]. Forensic Toxicology, 2024: 7-17. DOI: 10.1007/s11419-023-00670-0
[4] MONICA PATEL . Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists[J]. Biochemical pharmacology, 2020, 175: Article 113871. DOI: 10.1016/j.bcp.2020.113871
[5] K. MINAKATA. Sensitive quantification of 5F-PB-22 and its three metabolites 5F-PB-22 3-carboxyindole, B-22 N-5-hydroxypentyl and PB-22 N-pentanoic acid in authentic urine specimens obtained from four individuals by liquid chromatography–tandem mass spectrometry[J]. Forensic Toxicology, 2017, 36 1: 151-159. DOI: 10.1007/s11419-017-0395-4
[6] CLAUDIO ERRATICO. In vitro and in vivo human metabolism of the synthetic cannabinoid AB-CHMINACA[J]. Drug Testing and Analysis, 2015, 7 10: 866-876. DOI: 10.1002/dta.1796

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