118139-36-9

Name	Retin-20,20,20-d3-ol, 15-acetate
CAS	118139-36-9
Molecular Formula	C22H32O2
MDL Number	MFCD30738759
Molecular Weight	328.5
MOL File	118139-36-9.mol

Synonyms

ALK001 ALK-001 ALK 001 C-20D3vitamin A C-20-D3-vitamin A C-20-D3-Retinyl Acetate Retin-20,20,20-d3-ol, 15-acetate

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Hazard Information

Description

ALK-001 is a vitamin A analog potentially for the treatment of Stargardt’s disease.

Uses

Retinyl acetate-d3 (ALK-001) is a deuterated Vitamin A. Retinyl acetate-d3 can be used for research of geographic atrophy (GA) secondary to age-related macular degeneration (AMD)[1].

References

[1] Cargnin S, et al. A primer of deuterium in drug design. Future Med Chem. 2019 Aug;11(16):2039-2042. DOI:10.4155/fmc-2019-0183
[2] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110

Supplier

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Telephone17702719238

Websitehttp://www.sun-shinechem.com/

Artis Biotech Co. Ltd.

Telephone18108108965 18108108965

Websitehttps://artis-isotopes.com

Shandong Dayou Pharmaceutical Research and Development Co., Ltd.

Telephonedayouchem@126.com 15165037910

Website

TargetMol Chemicals Inc.

Telephone 15002134094

Websitehttps://www.targetmol.cn/

Hangzhou MolCore BioPharmatech Co.,Ltd.

Telephone+86-057181025280; +8617767106207

Websitehttps://www.molcore.com/

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