1173697-60-3

bpV(bipy) hydrate is the inhibitor for phosphoinositide 3-phosphatase (PTEN) and protein tyrosine phosphatases (PTP-β and PTP-1B) with IC50s of 18, 60.3, and 164 nM, respectively[1].

Cell permeable: no''Primary Target
phosphotyrosine phosphatase''Product does not compete with ATP.''Reversible: no''Target IC50: 18 nM against PTEN''Target Ki: 100 nM for phosphotyrosine phosphatase

[1] Schmid AC, et al., Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Lett. 2004 May 21;566(1-3):35-8. DOI:10.1016/j.febslet.2004.03.102