Chemical Properties
Coumafuryl is a colorless, white, crystalline solid or powder.
Potential Exposure
This material is an anticoagulant rodenticide. Therefore, those involved in its manufacture, formulation, and application are at risk.
First aid
If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 30 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Speed in removing material from skin is of extreme importance. Remove and isolate contaminated clothing and shoes at the site. Keep victim quiet and maintain normal body temperature. Effects may be delayed. Keep victim under observation.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3027 Coumarin derivative pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. At room temperature this material can decompose rapidly to cobalt carbonyl and hydrogen gas; at 52°C cobalt carbonyl decomposes, producing toxic fumes of cobalt and oxides of carbon
Description
Coumafuryl is an obsolete anticoagulant rodenticide. It is moderately soluble in water and is not volatile. Data suggests it is mobile and so it may have potential to leach to groundwater but its pattern of use would tend to significantly reduce the risk. Little is known about its toxicity to biodiversity. It is highly toxic to mammals via the oral route.
Definition
ChEBI: Coumafuryl is a hydroxycoumarin.
Production Methods
Coumafuryl is commercially produced through a condensation reaction between 4-hydroxycoumarin and 2-furylmethyl ketone. This synthesis typically occurs in the presence of a base such as sodium hydroxide and a solvent like ethanol or acetic acid, under controlled temperature conditions to facilitate the formation of the desired compound. After the reaction, the product is purified through crystallisation and drying to yield a white to off-white powder.
Mechanism of action
Anticoagulant - interferes with the production of blood clotting factors in the liver by blocking the action of vitamin K
Safety Profile
Poison by ingestion and possiblyother routes.
Pesticide Type
Rodenticide
