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20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.

ChEBI: 20beta-hydroxycortisone is a C21-steroid that is cortisone in which the oxo group at position 20 is replaced by a hydroxy group. It has a role as a human urinary metabolite. It is a C21-steroid, a 20-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 17alpha-hydroxy steroid and an 11-oxo steroid. It is functionally related to a cortisone. It derives from a hydride of a pregnane.