Hazard Information
Definition
PNC-27 is an anticancer peptide, containing an HDM-2-binding domain. PNC-27 shows anti-tumor activity and can be used in acute myeloid leukemia research.
in vitro
PNC-27 (50 μg/mL; 0-3 h) induces cancer cell death.
PNC-27 (50 μg/mL; 15 min) binds to cell membrane-bound HDM-2.
PNC-27 (50 μg/mL; 15 min) binds to cell membrane-bound HDM-2.
in vivo
PNC-27 (intraperitoneal injection; 40 mg/kg; once daily; 2-3 w) shows anti-leukemia activity in vivo.
Supplier
Wuxi Zhongkun Biochemical Technology Co., Ltd.
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Chengdu Youngshe Chemical Co., Ltd.
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Hangzhou Peptidego Biotech Co.,Ltd.
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Cellmano Biotech Limited
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Wuxi Helen Biotechnology Co., Ltd.,
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Hangzhou Go Top Peptide Biotech
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Molcoo Chemicals Inc.
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Nanjing Yuanpeptide Biotech Co.，Ltd.
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Sichuan Takele Biotechnology Co., Ltd.
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Hangzhou Baige Pharmaceutical Technology Co. , Ltd.
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Shanghai HongTide Biotechnology Co.,Ltd.
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Shanghai Weiyuxi Biotechnology Co. , Ltd.
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Shanghai Toyang Biotechnology Co., LTD
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Zhejiang Jiekun Biotechnology Co., Ltd
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Phygene
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