1155878-69-5

DChemsPC might be used:

• as a substitute for cholesterol in liposome formulation to study its effect on membrane stability
• in the preparation of pH-gradient liposomes
• to form sterol-phospholipid hybrid with palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine (PCholPC) and to study its properties and interactions

Liposome instability in blood is caused mainly due to cholesterol exchange. Sterol modified phospholipid retains the bilayer-stabilizing effect of free cholesterolinhibiting its transfer from the bilayer. Thereforedisterolphospholipids are ideal for liposome preparation. The use of DChemsPC in liposomes prevents content leaking into the serum.