113276-96-3

Valilactone is a fatty acid synthase inhibitor produced by a cultured strain of soil actinomycetes. Fatty acid synthase (FAS) is necessary for growth and survival of tumor cells and is a promising drug target for oncology.

Valilactone is a potent and effective inhibitor of esterase, produced by actinomycetes[1].

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[1] Kitahara M, et al. Valilactone, an inhibitor of esterase, produced by actinomycetes. J Antibiot (Tokyo). 1987;40(11):1647-1650. DOI:10.7164/antibiotics.40.1647