11062-03-6

ChEBI: ADP is a purine ribonucleoside 5'-diphosphate having adenine as the nucleobase. It has a role as a human metabolite and a fundamental metabolite. It is an adenosine 5'-phosphate and a purine ribonucleoside 5'-diphosphate. It is a conjugate acid of an ADP(3-) and an ADP(2-).

Proinsulin, a single-chain protein of 86 amino acid residues, is synthesized in the β cells and enzymatically transformed therein to insulin. The conversion involves the cleavage of a connecting C-peptide, which contains between 30 and 35 residues, with the number and sequence varying among different species (human C-peptide consists of 35 residues). The resulting human insulin consists of two peptide chains, designated A (having 21 residues) and B (having 30 residues), which are interchain connected by two disulfide bonds. Furthermore, the A-chain also contains an intrachain disulfide bond between Cys6 and Cys11.