106352-09-4

1,3-Dipalmitoleoyl glycerol is a diacylglycerol with palmitoleic acid at the sn-1 and sn-3 positions. It selectively inhibits α-glucosidase from S. cerevisiae over rat enzyme (IC₅₀s = 4.45 and 9,326.5 μM, respectively).¹ 1,3-Dipalmitoleoyl glycerol has been used in the formation of lipid bilayers to study the effects of membrane composition and the ionophore valinomycin on membrane potential.²

1,3-Dipalmitoleoyl glycerol (DG(16:1/0:0/16:1)) is a compound isolated from sea cucumber viscera, which has α-glucosidase inhibitory activity and has different degrees of inhibitory effects on α-glucosidase from different sources.

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1. Nguyen, T.H., and Kim, S.M. α-Glucosidase inhibitory activities of fatty acids purified from the internal organ of sea cucumber Stichopus japonicas J. Food Sci. 80(4),H841-H847(2015).
2. Minami, H., Sato, N., Sugawara, M., et al. Comparative study on the potentiometric responses between a valinomycin-based bilayer lipid membrane and a solvent polymeric membrane Anal. Sci. 7(6),853-862(1991).