105462-22-4

NE11808 is FPP synthase inhibitor.

NE11808 is a potent antiresorptive bisphosphonate that inhibits osteoclast prenylation and effectively inhibits protein prenylation in osteoclasts and suppresses labeling of dye-front end compounds.

[1] Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates PMID:11160603