ChemicalBook CAS DataBase List 1054-88-2

1054-88-2

Name	SPIROXATRINE
CAS	1054-88-2
Molecular Formula	C22H25N3O3
MDL Number	MFCD00055134
Molecular Weight	379.45
MOL File	1054-88-2.mol

Chemical Properties

Melting point	215.8-218.0 °C
Boiling point	602.8±55.0 °C(Predicted)
density	1.32±0.1 g/cm3(Predicted)
storage temp.	Store at RT
solubility	0.1 M HCl: moderately soluble
form	powder
pka	15.03±0.20(Predicted)
color	white

Safety Data

WGK Germany

Hazard Information

Spectrum Detail

Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0_EN.htm

Nanjing Chemlin Chemical Co., Ltd

Telephone025-83697070 13770331960

Websitehttp://www.echemlin.cn

Shaanxi Dideu Medichem Co. Ltd

Telephone +86-17392712779

Websitehttps://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-221/

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Telephone +8613580539051

Websitehttp://www.yuhengpharm.com/

Energy Chemical

Telephone400-0056266

Websitehttp://www.energy-chemical.com

TargetMol Chemicals Inc.

Telephone4008200310 15002144251

Websitehttps://www.targetmol.cn/

Shanghai Tachizaki Biomedical Research Center

Telephone 18014399201

Websitehttp://www.chemlab-tachizaki.com/

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Telephone6206333 13167063860

Websitehttp://www.aladdin-e.com/

Shanghai Amole Biotechnology Co., Ltd.

Telephone13370042665 18916960931

Websitehttps://www.amole.com.cn/

Guangzhou Ruidi Biotechnology Co., Ltd.

Telephone020-82099279 18988941402

Websitehttp://www.ubiochem.com/

Hangzhou MolCore BioPharmatech Co.,Ltd.

Telephone+86-057181025280; +8617767106207

Websitehttps://www.molcore.com/

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Animal Model:	The nerve injury rat model and Carrageenan (HY-125474)-induced rat inflammation model^[3]
Dosage:	1, 10, 25 ug, 5 days
Administration:	Intraperitoneal injection (i.p.)
Result:	Increased hindpaw withdrawal latencies to thermal and mechanical stimulation.

Animal Model:	Fluoxetine (HY-B0102) -induced reduction of ethanol Intake by the P Line of rats^[4]
Dosage:	4 mg/kg/day, 5 mins
Administration:	Intraperitoneal injection (i.p.)
Result:	Increased the voluntary oral ethanol intake induced by Fluoxetine (HY-B0102) in the selectively bred alcohol-preferring P line of rats.

1054-88-2

Chemical Properties

Safety Data

Hazard Information

Uses

Definition

Biological Activity

in vivo

IC 50

Spectrum Detail

Supplier

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