PPARγ agonist 8 is an agonist of PPARγ. PPARγ agonist 8 induces peroxisome proliferator response element (PPRE)-luciferase activity with an EC50 of 0.2 μM[1].
IC 50
PPARγ
References
[1] Felts AS, et.al. Sulindac derivatives that activate the peroxisome proliferator-activated receptor gamma but lack cyclooxygenase inhibition. J Med Chem. 2008 Aug 28;51(16):4911-9. DOI:10.1021/jm700969c