104615-18-1

Potent adenosine receptor antagonist

ChEBI: A member of the class of triazoloquinazolines that is [1,2,4]triazolo[1,5-c]quinazoline substited at positions 2, 5 and 9 by furan-2-yl, amino and chloro groups respectively. A potent antagonist at adenosine A1 and adenosi e A2A receptors.

Journal of Heterocyclic Chemistry, 27, p. 1549, 1990 DOI: 10.1002/jhet.5570270605

Potent adenosine receptor antagonist (K i values are 3.5, 4.2, 16 and 51 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively). Orally active in vivo .

CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity.

Store at RT