10380-41-3

2-Cyano-3,3-diphenylacrylic Acid was used to study skin-permeable selective cyclooxygenaswe-2 inhibitor composition, and to study hydrophilic components of cosmetic compositions, such as in sunscreen.

Within the human bodyOctocrylenea non-polar compoundundergoes metabolism to become a water-soluble metabolite 2-cyano-3,3-diphenylacrylic acidwhich is excreted through the kidneys. A pilot study in the general population has consistently detected CDAAand its levels have been linked to recent sunscreen application.