102616-64-8

Frataxin-in-1 (Compound (+)-11) is a Frataxin inhibitor with IC50 value of 45 μM, which can be used in the study of Friedreich's ataxia (FRDA)[1].

[1] Lavecchia A, et al. Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays. J Med Chem. 2013 Apr 11;56(7):2861-73. DOI:10.1021/jm3017199