Identification
Hazard Information
Supplier
my chemicalbook
En
中文
Sign in
Register
ChemicalBook
CAS DataBase List
1001083-74-4
1001083-74-4
Name
APcK110
CAS
1001083-74-4
Molecular Formula
C20H16FN3O2
Molecular Weight
349.36
MOL File
1001083-74-4.mol
Synonyms
APcK110
6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine
1H-Pyrazolo[3,4-b]pyridine, 6-(3,5-dimethoxyphenyl)-3-(4-fluorophenyl)-
show less
show more
Hazard Information
Uses
APcK 110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells.
in vivo
APcK110 (500 nM; i.p.; every other day for 60 days) shows anti-AML activity in mice
[2]
.
Animal Model:
Eight-weeks-old female NODSCID mice, OCI/AML3 xenograft mouse model
[2]
Dosage:
500 nM
Administration:
Intraperitoneal injection, every other day for 60 days
Result:
Survival of compound-treated mice was significantly longer compared with mice injected with PBS.
Supplier
Shanghai Hongye Biotechnology Co. Ltd
Telephone
400-9205774
Website
http://www.glpbio.cn/
TargetMol Chemicals Inc.
Telephone
15002134094
Website
https://www.targetmol.cn/
Hangzhou MolCore BioPharmatech Co.,Ltd.
Telephone
+86-057181025280; +8617767106207
Website
https://www.molcore.com/
PROMPT
×
PROMPT
The What'sApp is temporarily not supported in mainland China
Cancel
Determine
Send Inquriy
MSDS
|
CAS
|
CAS DataBase
|
Pricacy
|
Terms
|
About Us
|
New Products
|
Contact us
|
Computer Version
Chemical Book
