RAD140: Overview, Chemical Characteristics and Administration

General Description

RAD140 is a Selective Androgen Receptor Modulator that is currently being researched. It has gained popularity among bodybuilders and athletes due to its potent effects in stimulating muscle growth without the adverse side effects commonly associated with synthetic testosterone. RAD140 is being investigated for potential use in testosterone replacement therapy, as well as in treating muscle wasting and bone loss conditions. However, there is limited research on its efficacy and safety, and further studies are needed to fully understand its capabilities. Proper administration involves maintaining optimal levels of RAD140 in the bloodstream, with recommended cycles lasting 8 weeks followed by a break.

Figure 1. RAD140

Overview

RAD140, also known as Testolone, is an investigational Selective Androgen Receptor Modulator (SARM). Like all SARMs, RAD140 is still in the early stages of research and its potential as an approved drug for specific conditions is yet to be determined. Since 2020, it has been licensed to Ellipses Pharmaceuticals, a company dedicated to acquiring, developing, and conducting trials for promising drugs. Although the future of RAD140 remains uncertain, it has already gained popularity among bodybuilders and athletes due to its potent effects. Initially developed for potential use in testosterone replacement therapy, RAD140 aims to provide a safer alternative to synthetic testosterone, which often comes with adverse side effects. Additionally, like other SARMs, RAD140 is being explored for its potential in treating muscle wasting and bone loss conditions. To date, only one human study has been conducted with RAD140, spanning three years. This study focused on investigating RAD140 as a treatment for hormone receptor positive breast cancer in postmenopausal women. Due to the limited number of clinical studies conducted, there is still much unknown about the full capabilities, potential side effects, and long-term effects of RAD140. In conclusion, RAD140 is an experimental SARM currently undergoing research and development. While its powerful effects have garnered attention from bodybuilders and athletes, its efficacy and safety are yet to be fully understood. Further studies are needed to determine its potential applications and any associated risks. ¹

Chemical characteristics

RAD140 is a selective androgen receptor modulator (SARM) with distinct chemical characteristics. As a member of the SARM class, RAD140 exhibits properties similar to anabolic steroids, such as stimulating muscle growth through anabolic activity, while significantly reducing or even eliminating the risk of androgenic side effects. This unique attribute is attributed to its high selectivity in targeting androgen receptors, particularly in muscle and bone tissues. By primarily focusing on these specific receptors, RAD140 offers a valuable alternative for bodybuilders and athletes seeking to enhance performance and muscle development without enduring the harsh androgenic side effects commonly associated with traditional steroid use. The chemical structure of RAD140 enables it to exert its effects in a targeted and selective manner, making it a promising option for individuals looking to optimize their physical performance and muscle growth while minimizing potential adverse effects. ²

Administration

Proper administration of RAD140 involves maintaining optimal levels of this SARM in your bloodstream. It is unnecessary to split the dose for twice daily administration, as a single dose is sufficient. The timing of administration is a personal choice, with most individuals opting to take it either in the morning or about an hour before their workout. The standard RAD140 cycle typically lasts 8 weeks, followed by a minimum 5-week break without RAD140 or any other SARM. It is recommended to take an 8-week break, especially after using higher doses. Men may need post-cycle therapy during this break to restore testosterone function. For advanced users, particularly in cutting cycles and contest preparation, a 6-week RAD140 cycle at a higher dose is common. Some experienced users may extend the cycle to 10 weeks, although this is considered an advanced strategy and not advisable for beginners or those without prior experience with RAD140. ¹

Reference

1. Juice. RAD-140 (Testolone). 2023. Steroid cycle.

2. Testolone. National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 44200882.

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