aladdin 阿拉丁 I127961 伊立替康 97682-44-5 ≥99%

中文名：伊立替康

英文名：Irinotecan

中文别名：伊立替康

英文别名：MFCD00866307|AB00698464-10|CPT-11|D08086|(+)-7-ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate|[1,4'']Bipiperidinyl-1''-carboxylic acid 4,11-diethyl-4-hydroxy-3,13-dioxo-3,4,12,13-tetrahydro-1H-2-oxa-6,12a-diaza-dibenzo[b,h]fluoren-9-y

纯度：≥99%

货号：I127961

包装：100mg、500mg

Cas号：97682-44-5

存储温度：2-8°C储存

产品介绍：

Irinotecan是一种Topoisomerase I抑制剂，作用于LoVo细胞和HT-29细胞，IC50分别为15.8 μM和5.17 μM。

Irinotecan hydrochloride has been used:

in combination with 5-fluorouracil for screening growth inhibitory functionality in MDA-MB-231 breast cancer cells.

in chemosensitivity screening of high-grade appendiceal (HGA) and low-grade appendiceal (LGA) organoids.

as a chemotherapeutic agent in the cytotoxicity studies in combination with heat shock proteins inhibitors (HPSC1) in HT29 colon cancer cells.

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