アルミニウム オキシド

外観

白色〜ほとんど白色, 粉末

定義

本品は、天然のサファイアに類似するように合成された赤以外の色を持つ白色から黒色の化合物である。

溶解性

水, 酸に不溶。水及び酸にほとんど溶けない。

解説

酸化アルミニウム，アルミナともいう．天然にはコランダム(鋼玉)として産出する．金剛砂は不純物を含んだもので，ルビーやサファイアは微量の重金属を含んだものである．ボーキサイト，ギブス石，ダイアスポアは水和物である．いくつかの変態があるが，いずれも無色で水には溶けず，鉱酸や強アルカリにも難溶であり，燃焼性や毒性はない．熱的に非常に安定である．両性酸化物だが，強熱したものは酸に難溶となり，融解したものは硬度が大きく，耐火性にもすぐれている．アルミン酸塩水溶液の加水分解により各種の水和酸化アルミニウムが得られる．水和酸化アルミニウムを高温で脱水すると安定なα-アルミナを生じる．α-アルミナは，密度3.9 g cm－3．融点2015±15 ℃，沸点2980±60 ℃．水に不溶．モース硬さ9．脱水温度が300 ℃ より低いと準安定なγ-アルミナが生成する．γ-アルミナは密度3.5～3.9 g cm－3．吸湿性で，軟らかい．さらに低温で脱水したものが活性アルミナで，表面積がきわめて大きいために吸着剤，乾燥剤などとして用いられる．触媒，半導体，研磨剤，工具研削剤，耐熱剤，絶縁体，レーザー材料，模造宝石，ガラス繊維，ニューセラミックス原料などに用いられる．

用途

研磨剤。

用途

精密な研磨用。

用途

アルミニウム電解用、触媒、触媒担体、耐火物、セラミック原料、研削砥石、高アルミナ質耐火煉瓦、高級耐火物の骨材、研磨材、蒸着、結晶育成原料、半導体製造、化粧品原料

用途

カテコールアミン吸着剤。

用途

研磨剤、砥石、耐火物、絶縁物等。

用途

耐火剤、磁器材料、セラミック材料。

化粧品の成分用途

不透明化剤、滑沢剤、抗ケーキング剤、吸着剤、研磨.スクラブ剤、増量剤

説明

Aluminum(III) oxide is also called aluminum oxide. In mineral form it is called corundum and is referred to as alumina in conjunction with mining and aluminum industries. Alumina exists in hydrated forms as alumina monohydrate, Al₂O₃?H₂O and alumina trihydrate Al₂O₃?3H₂O. The geologic source of aluminum is the rock bauxite, which has a high percentage of hydrated aluminum oxide. The main minerals in bauxite are gibbsite (Al(OH)₃), diaspore (AlO(OH)), and boehmite (AlO(OH).

化学的特性

Aluminum oxide occurs as a white crystalline powder. Aluminum oxide occurs as two crystalline forms: α-aluminum oxide is composed of colorless hexagonal crystals, and γ-aluminum oxide is composed of minute colorless cubic crystals that are transformed to the α-form at high temperatures.

物理的性質

Al2O3 Colorless hexagonal crystal; refractive index 1.768; density 3.965 g/cm3 (at 25°C); mp 2072°C; bp 2980°C; insoluble in water α-Al2O3 Colorless rhombic crystal; mp between 2005 to 2025°C ; density 4.022 g/m3 ; hardness 9Moh γ-Al2O3 white microscopic crystal Al2O3•H2O colorless rhombic crystal; refractive index 1.624; density 3.014 g/cm3 Al2O3•3H2O white monoclinic crystal; refractive index 1.577; density 2.420 g/cm3 All forms are insoluble in water.

物理的性質

White and translucent hard material used as abrasive for grinding. Excellent electric insulator and also wear resistant. Insoluble in water and in strong mineral acids, readily soluble in strong alkali hydroxides, attacked by HF or NH₄HF₂. Owing to its corrosion resistance, in inert atmosphere, in molten metals such as Mg, Ca, Sr, Ba, Mn, Sn, Pb, Ga, Bi, As, Sb, Hg, Mo, W, Co, Ni, Pd, Pt, and U it is used as crucible container for these liquid metals. Alumina is readily attacked in an inert atmosphere by molten metals such as Li, Na, Be, Al, Si, Ti, Zr, Nb, Ta, and Cu. Maximum service temperature 1950°C

天然物の起源

Occurs in nature in abundance; the principal forms are bauxites and laterites. The mineral corundum is used to produce precious gems, such as ruby and sapphire. Activated aluminas are used extensively as adsorbents because of their affinity for water and other polar molecules; and as catalysts because of their large surface area and appropriate pore sturcture. As adsorbents, they are used for drying gases and liquids; and in adsorption chromatography. Catalytic properties may be attributed to the presence of surface active sites (primarily OH^- , ^O2- , and Al³⁺ ions). Such catalytic applications include sulfur recovery from H₂S (Clauss catalysis); dehydration of alcohols, isomerization of olefins; and as a catalyst support in petroleum refining.

特性

Aluminum Oxide (Alumina) is the most widely used oxide, chiefly because it is plentiful, relatively low in cost, and equal to or better than most oxides in mechanical properties. Density can be varied over a wide range, as can purity — down to about 90% alumina — to meet specific application requirements. Alumina ceramics are the hardest, strongest, and stiffest of the oxides. They are also outstanding in electrical resistivity, dielectric strength, are resistant to a wide variety of chemicals, and are unaffected by air, water vapor, and sulfurous atmospheres. However, with a melting point of only 2039°C, they are relatively low in refractoriness, and at 1371°C retain only about 10% of room-temperature strength. In addition to its wide use as electrical insulators and its chemical and aerospace applications, the high hardness and close dimensional tolerance capability of alumina make this ceramic suitable for such abrasion-resistant parts as textile guides, pump plungers, chute linings, discharge orifices, dies, and bearings.

使用

• As adsorbent, desiccant, abrasive,thickening and anti-caking agent;
• As filler for paints and varnishes;
• In manufacture of alloys,refractories, ceramic materials, electrical insulators and resistors, dental cements, glass, steel, artificial gems; in coatings for metals, etc.;
• As catalyst for organic reactions.
• As an insoluble carrier for mineral pigment, and is frequently mixed into mineral powder makeup. Because of its abrasive texture, many use these crystals to exfoliate and resurface the skin-particularly with Microdermabrasion.
• As a chromotagraphic matrix; originally called Brockmann aluminum oxide when used for this purpose.
• The minerals corundum (hardness = 9) and Alundum (obtained by fusing bauxite in an electric furnace) are used as abrasives and polishes;
• In manufacture of cosmetic products like blush, powder foundation, lipstick and facial cleanser.

製造方法

Pure Aluminum oxide, needed to produce aluminum by the Hall process, is made by the Bayer process. The starting material is bauxite (Al2O3 • nH2O). The ore contains impurities, such as, SiO2, Fe2O3, TiO2, and Na2O. Most impurities are removed following treatment with caustic soda solution. Bauxite is dissolved in NaOH solution. Silica, iron oxides and other impurities are filtered out of the solution. CO2 is then bubbled through this solution. This precipitates are heated to remove water and produce Al2O3. These impurities are removed. Calcinations of bauxite produce Aluminum oxide of abrasive and refractory grades. Activated Aluminum oxide of amorphous type, as well as the transition Aluminum oxides of γ, η, χ, and ρ forms, are obtained from various aluminum hydroxides, such as, α- and β-trihydrates, α-monohydrate and Aluminum oxide gel. Such chemicals are also obtained from bauxite by the Bayer process.

定義

The mineral corundum is natural aluminum oxide, and emery, ruby, and sapphire are impure crystalline varieties. The mixed mineral bauxite is a hydrated aluminum oxide.

調製方法

The Bayer process begins by grinding the bauxite and mixing it with sodium hydroxide in a digester. The sodium hydroxide dissolves aluminum oxide components to produce aluminum hydroxide compounds. For gibbsite, the reaction is: Al(OH)₃ + NaOH → Al(OH)₄^- + Na⁺. Insoluble impurities such as silicates, titanium oxides, and iron oxides are removed from the solution while sodium hydroxide is recovered and recycled. Reaction conditions are then modified so that aluminum trihydroxide (Al(OH)₃) precipitates out. The reaction can be represented as the reverse of the previous reaction: Al(OH)₄^- + Na⁺ → Al(OH)₃ + NaOH. Aluminum trihydroxide is calcined to drive off water to produce alumina:
Al(OH)₃ Al₂O₃ + 3H₂O.

反応性

Aluminum oxide exhibits amphoteric behavior. It is soluble both in acids and bases. With acids, it produces their corresponding salts. It froms Al2(SO4)3, Al(NO3)3 and AlCl3 upon reactions with H2SO4, HNO3, and HCl, respectively. In acid medium, it exists as a solvated aluminum ion, in which water molecules are hexacoordinated to trivalent Al3+, as shown below:
Al2O3 + 6H3O+3H2O ——› 2[Al(H2O)6]3+
(Rollinson, C. L., 1978., Aluminum Compounds. In Kirk-Othmer Encyclopedia of Chemical Technology, 3rd ed. Vol 2, pp 188-97. NY,: Wiley Interscience)
Aluminum oxide forms hydroxide in aqueous alkaline solution. The reaction is slow. The products, aluminum hydroxides (hydrated aluminas), contain hexacoordinated aluminohydroxide anion:
Al2O3 + 2OH– + 7H2O → 2[Al(OH)4(H2O)2]–
In its dry state, Aluminum oxide exhibiting basicity reacts with silica, forming aluminum silicate
Al2O3 + 3SiO2 → Al2(SiO3)3
Similarly, with basic CaO or MgO aluminate salts are formed
MgO + Al2O3 → Mg(AlO2)2 CaO + Al2O3 → Ca(AlO2)2
It forms aluminum nitride, AlN when heated with coal in a stream of nitrogen; and aluminum borate, Al2O3 •B2O3 when heated with B2O3 at 1000°C.

一般的な説明

White odorless crystalline powder. Water insoluble. Properties (both physical and chemical) vary according to the method of preparation; different methods give different crystalline modifications. The variety formed at very high temperature is quite inert chemically.

空気と水の反応

Insoluble in water.

反応プロフィール

Aluminum oxide is chemically amphoteric (behaves as a weak acid in the presence of base and as a weak base in the presence of acid). May act catalytically. May cause the exothermic polymerization of ethylene oxide. May cause the vigorous polymerization of vinyl chloride [MCA SD-75, 1970]. The degree of subdivision of the Aluminum oxide may affect the vigor of such reactions.

危険性

Toxic by inhalation of dust. Confirmed car- cinogen.

健康ハザード

The aluminas are considered to be nuisance dusts; their role in fibrogenic lung disease remains unclear.
Assessment of the toxicity of aluminas has been complicated by the chemical and physical variants of the compounds and inconsistencies in the nomenclature used to describe them.1 The group of compounds referred to as aluminas is composed of various structural forms of aluminum oxide, trihydroxide, and oxyhydroxide. 2 As these aluminas are heated, dehydration occurs, producing a variety of transitional forms; temperatures between 200 and 500°C result in low-temperature-range transitional aluminas characterized by increased catalytic activity and larger surface area.(Transitional aluminas include c, h, and g forms, which, taken together, were formerly termed “g.”)

応用例（製薬）

Aluminum oxide is used mainly in tablet formulations.It is used for decoloring powders and is particularly widely used in antibiotic formulations. It is also used in suppositories, pessaries, and urethral inserts. Hydrated aluminum oxide is used in mordant dyeing to make lake pigments, in cosmetics, and therapeutically as an antacid.

安全性プロファイル

Suspected carcinogen with experimental neoplastigenic and tumorigenic data by implantation. Inhalation of finely divided particles may cause lung damage (Shaver's disease). Exothermic reaction above 200℃ with halocarbon vapors produces toxic HCl and phosgene. See also ALUMINUM COMPOUNDS

安全性

Aluminum oxide is generally regarded as relatively nontoxic and nonirritant when used as an excipient. Inhalation of finely divided particles may cause lung damage (Shaver's disease).
HUMAN HEALTH RISK ASSESSMENT FOR ALUMINIUM, ALUMINIUM OXIDE, AND ALUMINIUM HYDROXIDE

職業ばく露

Most hazardous exposures to aluminum occur in smelting and refining processes. Aluminum is mostly produced by electrolysis of Al2O3 dissolved in molten cryolite (Na3AlF6). Aluminum is alloyed with copper, zinc, silicon, magnesium, manganese, and nickel; special additives may include chromium, lead, bismuth, titanium, zirconium, and vanadium. Aluminum and its alloys can be extruded or processed in rolling mills, wire works, forges, or foundries; and are used in the shipbuilding, electrical, building, aircraft, automobile, light engineering, and jewelry industries. Aluminum foil is widely used in packaging. Powdered aluminum is used in the paints and pyrotechnic industries. Alumina, emery, and corundum has been used for abrasives, refractories, and catalysts; and in the past in the first firing of china and pottery.

貯蔵

Aluminum oxide should be stored in a well-closed container in a cool, dry, place. It is very hygroscopic.

輸送方法

UN1309 Aluminum powder, coated, Hazard Class: 4.1; Labels: 4.1-Flammable solid. UN1383 Pyrophoric metals, n.o.s. or Pyrophoric alloys, n.o.s., Hazard Class: 4.2; Labels: 4.2-Spontaneously combustible material, Technical Name Required. UN1396 Aluminum powder, uncoated, Hazard Class: 4.3; Labels: 4.3-Dangerous when wet material. NA9260 (North America) Aluminum, molten, Hazard class: 9; Labels: 9-Miscellaneous hazardous material.

純化方法

Stir the oxide with hot 2M HNO3, either on a steam bath for 12hours (changing the acid every hour) or three times for 30minutes, then wash it with hot distilled water until the washings have pH 4, and follow by three washings with hot MeOH. The product is dried at 270o [Angyal & Young J Am Chem Soc 81 5251 1959]. For the preparation of alumina for chromatography see Chapter 1. [For  ,  and  Al2O3 see Becher in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I p 822-823 1963 and Wagner in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol II p 1662 1965.]

不和合性

Aluminum oxide should be kept well away from water. It is incompatible with strong oxidizers and chlorinated rubber. Aluminum oxide also reacts with chlorine trifluoride, ethylene oxide, sodium nitrate, and vinyl acetate. Exothermic reactions above 2008℃ with halocarbon vapors produce toxic hydrogen chloride and phosgene fumes.

廃棄物の処理

Consult with environmental regulatory agencies for guidance on acceptable disposalpractices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal of Aluminum Oxide-Disposal in a sanitary landfill. Mixing of industrial process wastes and municipal wastes at such sites is not encouraged however. Aluminum powder may be recovered and sold as scrap. Recycling and recovery is a viable option to disposal for aluminum metal and aluminum fluoride (A-57).

規制状況(Regulatory Status)

Included in the FDA Inactive Ingredients Database (oral tablets and topical sponge). Included in nonparenteral medicines licensed in the UK.