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外観
白色の粉末
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溶解性
アセトンに溶けやすく、水にほとんど溶けない。
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農薬用途
殺菌剤
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説明
Famoxadone is an oxazolidinedione
fungicide. Although famoxadone is not a strobilurin
derivative, it shares the same mechanism of action. Famoxadone provides control of a broad spectrum of
fungi but is particularly effective against downy mildew
(P. viticola), late and early blights (Phytophthora infestans
and Alternaria solani), the Septoria complex, and barley
net blotch at rates of 50 to 200 g ai/ha. Target crops include
vines, potatoes/tomatoes, cereals, sugar beets, canola, and
cucumber. It shows good protectant, translaminar and residual control, with excellent rainfastness and good crop
safety. As was seen for trifloxystrobin, it is particularly
effective against grape downy mildew when applied in
mixture with cymoxanil. The cereal disease spectrum and
level of disease control are improved when famoxadone is
mixed with triazole fungicides such as flusilazole.
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化学的特性
Brown Solid
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使用
Famoxadone is a known fungicide used in the protection of agricultural products against various fungal diseases and other biotic stresses such as pests.
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农业用途
Fungicide: Tanos 50-DF is recommended for use as a preventative
fungicide for control of late blight and early blight on
potatoes and field tomatoes.
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製品名
DPX-JE874®; FAMOXATE®; MEDLEY®;
TANOS-50DF®
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薬理学
Famoxadone inhibits activity of ubiquinol : cytochrome
c oxidoreductase at the Qo site of complex III,
the same target protein as the strobilurins (34,35). However,
studies show a difference in the potency of various
strobilurins compared with famoxadone in single amino
acid mutants of the cytochrome b protein, suggesting that
this compound may interact differently with the target
protein (38).
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代謝経路
Famoxadone undergoes extensive degradation and metabolism in aqueous
and soil environments, in wheat plants, rats, goats and hens via common
pathways. The primary reactions include the hydrolytic opening of
the oxazolidinedione ring, aryl hydroxylation, cleavage of the phenoxyphenyl
and the oxazolidinedione-aminophenyl linkages and conjugation.
More than 25 degradation products have been identified.
