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外観
白色〜わずかにうすい褐色, 結晶性粉末〜粉末
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溶解性
エタノール及びアセトンに溶け、水に溶けない。
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農薬用途
殺菌剤
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使用上の注意
アルゴン封入
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化学的特性
Off-White Solid
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使用
Quinoxyfen is under development for the control of powdery
mildew in cereals and grapes.
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定義
ChEBI: A member of the class of quinolines carrying two chloro substituents at positions 5 and 7 together with a 4-fluorophenoxy substituent at position 4. A fungicide used mainly to control powdery mildew in cereals.
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環境運命予測
The stability of quinoxyfen in the soil has been shown
to vary depending on soil type and source. DT50 values
obtained in the field varied from 5 to 454 days for a
range of soil types. The strong adsorptive properties of
quinoxyfen reduce its soil dissipation rate, but result in
no leaching potential of this fungicide into waterways or
groundwater. The primary metabolite formed in the soil is
3-hydroxyquinoxyfen . A secondary soil metabolite
is 5,7-dichloro-4-hydroxyquinoline (DCHQ). DCHQ was
also found not to leach, even in sandy soils. Under acidic
aqueous conditions, DCHQ was the primary metabolite
found, and this was produced in greater quantities at
acidic pHs. An additional metabolite was isolated from
both water and the sediment in an aqueous clay loam
system. Although not positively identified, it is suspected
to be 6-hydroxyquinoxyfen.
A similar hydrolysis profile is observed in water
as in soil (3). The primary product produced under
acidic conditions in the absence of light was DCHQ.
However, in the presence of light, photolysis was greatly
increased and dose dependent on the amount of sunlight
received. The primary photolysis product was 2-chloro-10-
fluoro[1]benzopyrano[2,3,4-de]quinoline (CFBPQ).
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代謝経路
Quinoxyfen is a novel fungicide for the control of powdery mildew in
cereals. Its mode of action is unknown but it appears to differ from those
of current fungicides and thus may be novel (Longhurst et al., 1996).
Quinoxyfen is tightly bound to soil components and is somewhat persistent
in this medium but in aqueous solution it is subject to rapid
photodecomposition. Photodegradation is therefore likely to be an important
process in its immediate removal from the environment. Plant
metabolites have not been reported but unchanged quinoxyfen has been
confirmed as the major residue.
The compound is rapidly metabolised and eliminated following ingestion
by rats and goats. Metabolism involves mainly hydroxylation of the
intact quinoxyfen, cleavage at the ether bond and conjugation of the
resulting metabolites. The information presented below was obtained
from two sources (DowElanco, 1996; Reeves et al., 1996).
