8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA. It acts to promote hatching of barnacle eggs at 10 nM, although it is not clearly identified as the natural egg hatching factor.1
References
1. Hill, E.M., Holland, D.L., Gibson, K.H., et al. Identification and hatching factor activity of monohydroxyeicosapentaenoic acid in homogenates of the barnacle Elminius modestus Proc. R. Soc. Lond. B Biol. Sci. 234,455-461(1988).
