ピゾチフェン

外観

白色～ほとんど白色粉末～結晶

効能

タンパク同化薬, 抗うつ薬, 抗片頭痛薬, セロトニン受容体拮抗薬

化学的特性

White to Off-White Solid

使用

Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant.

適応症

Pizotifen, a potent antihistamine and antiserotonin agent usually prescribed for migraine prophylaxis, has had reported success in patients with polycythemia vera.

定義

ChEBI: A benzocycloheptathiophene that is 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophene 4-ylidene)-1-methylpiperidine which is joined from the 4 position to the 4 position of an N-methylpiperidine moiety b a double bond. It is a sedating antihistamine, with strong serotonin antagonist and weak antimuscarinic activity. It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods.