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外観
白色～わずかにうすい褐色, 結晶性粉末
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定義
本品は、アスコルビン酸(*)の異性体であり、次の化学式で表される。
参照表示名称：アスコルビン酸
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溶解性
水に溶けやすく、エタノールにやや溶けにくく、アセトンに溶けにくい。
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化粧品の成分用途
酸化防止剤、香料
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化学的特性
Erythorbic acid occurs as a white or slightly yellow-colored crystals
or powder. It gradually darkens in color upon exposure to light.
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使用
Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150–200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%.
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調製方法
Erythorbic acid is synthesized by the reaction between methyl 2-
keto-D-gluconate and sodium methoxide. It can also be synthesized
from sucrose, and produced from Penicillium spp.
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応用例（製薬）
Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as
an antioxidant in foods and oral pharmaceutical formulations. It
has approximately 5% of the vitamin C activity of L-ascorbic acid.
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安全性
Erythorbic acid is widely used in food applications as an
antioxidant. It is also used in oral pharmaceutical applications as
an antioxidant. Erythorbic acid is generally regarded as nontoxic
and nonirritant when used as an excipient. Erythorbic acid is readily
metabolized and does not affect the urinary excretion of ascorbic
acid.
The WHO has set an acceptable daily intake of erythorbic acid
and its sodium salt in foods at up to 5 mg/kg body-weight.
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貯蔵
Erythorbic acid should be stored in an airtight container, protected
from light, in a cool, dry place.
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純化方法
Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.]
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不和合性
Erythorbic acid is incompatible with chemically active metals such
as aluminum, copper, magnesium, and zinc. It is also incompatible
with strong bases and strong oxidizing agents.
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規制状況(Regulatory Status)
GRAS listed. Accepted for use as a food additive in Europe.
Included in the FDA Inactive Ingredients Database (oral concentrate
and tablets).
