(+)-脱落酸
(+)-脱落酸 性质
熔点 | 188 °C |
---|---|
比旋光度 | D20 +411.1° (c = 1 in ethanol); D20 +426.5° (c = 1 in 0.005N methanolic H2SO4) |
沸点 | 327.55°C (rough estimate) |
密度 | 1.0583 (rough estimate) |
折射率 | 410 ° (C=0.2, EtOH) |
储存条件 | 2-8°C |
溶解度 | 氯仿(微溶)、乙醇(微溶)、甲醇(微溶) |
酸度系数(pKa) | 4.87±0.33(Predicted) |
形态 | 类白色粉末 |
颜色 | 白色至浅黄色 |
旋光性 (optical activity) | [α]/D 415±10°, c = 0.1 in ethanol |
Merck | 14,11 |
BRN | 2698956 |
稳定性 | 感光 |
InChIKey | JLIDBLDQVAYHNE-WEYXYWBQSA-N |
LogP | 1.896 (est) |
CAS 数据库 | 21293-29-8(CAS DataBase Reference) |
EPA化学物质信息 | 2,4-Pentadienoic acid, 5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-, (2Z,4E)- (21293-29-8) |
(+)-脱落酸 用途与合成方法
Human Endogenous Metabolite
|
In Arabidopsis cell cultures, Abscisic acid ((S)-(+)-Abscisic acid; 10 μM) simultaneously induces rapid alkalinization of the medium and plasma membrane depolarization.
Abscisic acid (10 μM) increases Ca
2+
in cytosol of Arabidopsis cell suspension. Abscisic acid does not inhibit proton pumping directly but through an increase in cytosolic Ca
2+
.
Lanthionine synthetase C-like 2 (LANCL2) is the natural receptor for Abscisic acid. Abscisic acid, both at the organism levels and in specific muscle cells ex vivo, increases both glucose and fatty acid metabolism in the mitochondria, increases glycogen synthesis, activates PI3K independently of insulin and promotes GLUT4 translocation to the cell membrane.
Abscisic acid (orally; 0.125 µg/kg/day; for 12 weeks) improves glycemic control.
Abscisic acid (orally; 0.125 µg/kg/day; for 12 weeks) results in significantly lower levels of TNF, MCP-1 and IL-6 in the DIO model. Abscisic acid increases metabolic activity in skeletal muscle.
Animal Model: | Diet-induced obesity (DIO) mice at 4 weeks of age |
Dosage: | 0.125 µg/kg |
Administration: | Orally; daily; for 12 weeks |
Result: | Improved glycemic control in a diet-induced model of obesity |
(+)-脱落酸 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024-01-16 | XW212932986 | (+)-脱落酸 | 21293-29-8 | 100MG | 93 |
2024-01-16 | S7594 | (+)-脱落酸 | 21293-29-8 | 5mg | 809.55 |