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外観
無色～うすい黄褐色、澄明の液体
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溶解性
エタノールに溶け、水に溶けにくい。エタノールに可溶。溶液は紫色のケイ光を発する。
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化学的特性
Ethyl anthranilate has a faint, orange-flower odor and similar taste.
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天然物の起源
Reported found in grapes, orange juice, orange peel oil, starfruit and Vitis labrusca L.
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使用
Perfumery and flavors, similar to methyl
anthranilate.
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製造方法
By esterification of anthranilic acid with ethanol in the presence of acid catalysts; by reacting sodium hypochlorite with
an alkaline solution of phthalimide
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一般的な説明
Colorless liquid with a fruity odor. Insoluble in water.
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空気と水の反応
ETHYL ANTHRANILATE should be protected from air and light. Insoluble in water.
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反応プロフィール
ETHYL ANTHRANILATE may hydrolyze under acidic and basic conditions.
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火災危険
Flash point data for ETHYL ANTHRANILATE are not available. ETHYL ANTHRANILATE is probably combustible.
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薬理学
Ethyl anthranilate behaved as a local anaesthetic, as measured by depression of
muscle twitch, but was 50% less effective than the m- and p-aminobenzoate isomers. All three compounds
potentiated the initial phase of caffeine-induced contracture of frog sartorius muscle, but
the o-isomer had no effect on the peak tension of the contracture (Friedman, Bianchi & Weiss.
1974). It was proposed that the o-amino group has both steric and polar effects, its bulk preventing
the inhibitory action of the carbonyl group on the caffeine-induced contracture of sartorius muscle,
while the lone electron pair of the nitrogen atom induces a contracture on its own accord and
potentiates a caffeine-induced contracture (Friedman, 1975).
Ethyl anthranilate (0-1 mmol/litre) decreased the frequency of the electric-organ discharges of
the electric fish, Gnathonemus moori, but did not affect the individual pulse amplitudes, indicating
that the compound acted on the pacemaker cells of the mesencephalic command nucleus (Walsh
& Schopp, 1966).
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安全性プロファイル
Moderately toxic by
ingestion. A skin irritant. Combustible
liquid. When heated to decomposition it
emits toxic fumes of NOx.
