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定義
本品は、ハイマツPinus pumilio の葉又は球果から得られる精油である。
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化粧品の成分用途
香料
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化学的特性
Dwarf-pine-needle oil is obtained in Austria (Tyrol) and other
mountainous areas of Central and Southeast Europe by steam distillation of
fresh needles and twig tips of Pinus mugo Turra ssp. mugo and ssp. pumilio
(Haenke) Franco. It is a colorless liquid with a pleasant, balsamic odor.
d2020 0.858–0.868; n20D 1.474–1.478; α20D ?15 ° to ?7 °; solubility: 1 vol in
≤10 vol of 90% ethanol. Content by GC: α-pinene 10–30%;β-pinene 3–14%; 3-carene 5–25%; β-phellandrene 8–17%; limonene 8–14%; bornyl acetate 1–5%.
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物理的性質
It is a clear, almost colorless, mobile liquid.
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天然物の起源
Found in the branches and adherent leaves of P. mugo Turra var. pumilio (Fam. Pinaceae) (Guenther, 1952).
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製造方法
By steam distillation of the branches and leaves of P. mugo Turra var. pumilio (Guenther, 1952).
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精油の成分
Main constituents include l-α-pinene, β-pinene, l-limonene, dipentene, l-phellandrene, aldehydes, various
esters, and alcohols.
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薬理学
In man. Pinus pumilio oil increased bronchial secretions (Thomas, 1958). A dose
of 500 mg/kg was reported to have no effect in vivo on the metabolism and pharmacological activity
of pentobarbitone (25 mg/kg) in rats or in vitro on the metabolism of amidopyrene, p-nitroanisole
and aniline by rat liver (Jori et al. 1969). Intravenous injection of the oil dissolved in sorbitol
monostearate water caused no toxic effects in warm-blooded animals and large doses caused no
changes in blood pressure, but it showed digitalis-like action of the isolated toad heart (Primavori.
1960).
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安全性プロファイル
Mildly toxic by
ingestion. A human skin irritant. When
heated to decomposition it emits acrid
smoke and irritating fumes.
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代謝
Following immersion of young pigs and one human subject for 30 min in baths containing 150 ml of a pine-oil mixture (Fichtennadel-Latschenkiefer?l. Kneipp) in 450 litres of water, a- and ?-pinene and limonene (components of Latschenkiefer?l) were detected in the exhaled air within 20 min, reaching maximum levels 50-75 min after the start of the bath and remaining detectable after 1 day (R?mmelt, Zuber. Dirnagl. & Drexel. 1974).
