クロルジアゼポキシド·塩酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

• 注意書き

  P201：使用前に取扱説明書を入手すること。

  P308+P313：暴露または暴露の懸念がある場合：医師の診断/手当てを 受けること。

クロルジアゼポキシド·塩酸塩 価格

クロルジアゼポキシド·塩酸塩 化学特性,用途語,生産方法

• 効能

  催眠鎮静薬

• 化学的特性

  white crystalline powder

• 使用

  Sedative-hypnotic.

• 一般的な説明

  Chlordiazepoxide hydrochloride, 7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepine4-oxide monohydrochloride (Librium), is well absorbedafter oral administration. Peak plasma levels are reachedin 2 to 4 hours. The half-life of chlordiazepoxide is 6 to30 hours. N-demethylation and hydrolysis of the condensedamidino group are rapid and extensive, producing demoxepamas a major metabolite. Demoxepam can undergo fourdifferent metabolic fates. It is converted principally to itsactive metabolite nordazepam, which is also a major activemetabolite of diazepam, clorazepate, and prazepam.Nordazepam, in turn, is converted principally to active oxazepam(marketed separately), which conjugated to the excretedglucuronide. Because of the long half-life of parentdrug and its active metabolites, this drug is long acting andself-tapering. As with diazepam (vide infra), repeated administrationof chlordiazepoxide can result in accumulationof parent drug and its active metabolites, and thus cause excessivesedation.

• 空気と水の反応

  Slightly soluble in water.

• 反応プロフィール

  Acidic salt of an amine. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

• 危険性

  CNS depressant. Manufacture and dosage controlled by law.

• 火災危険

  Flash point data for CHLORDIAZEPOXIDE HYDROCHLORIDE are not available. CHLORDIAZEPOXIDE HYDROCHLORIDE is probably combustible.

• 安全性プロファイル

  Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Human systemic effects: ataxia, dlstorted perceptions, hallucinations, somnolence, and surface EEG changes. Mutation data reported. A minor tranquhzer. When heated to decomposition it emits very toxic fumes of HCl and NOx.

クロルジアゼポキシド·塩酸塩 上流と下流の製品情報

クロルジアゼポキシド·塩酸塩 生産企業

Global(61)Suppliers

クロルジアゼポキシド·塩酸塩 スペクトルデータ(IR1、IR2、MS)

438-41-5, クロルジアゼポキシド·塩酸塩 キーワード