2,4-ジニトロトルエン

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Danger

• 危険有害性情報

  H341：遺伝性疾患のおそれの疑い

  H350：発がんのおそれ

  H373：長期にわたる、または反復暴露により臓器の障 害のおそれ

  H410：長期的影響により水生生物に非常に強い毒性

• 注意書き

  P201：使用前に取扱説明書を入手すること。

  P273：環境への放出を避けること。

  P280：保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

2,4-ジニトロトルエン 価格

MSDS Information

• 1-Methyl-2,4-Dinitrobenzene

2,4-ジニトロトルエン 化学特性,用途語,生産方法

• 外観

  ほとんど白色〜うすい黄色, 結晶〜粉末

• 溶解性

  エタノール及びアセトンに溶ける。

• 解説

  2,4-ジニトロトルエン．トルエンを発煙硝酸でジニトロ化すると得られる．黄色の針状晶．融点71 ℃，分解点300 ℃．d⁷¹1.3208．n_D1.442．エタノール，エーテル，アセトン，ベンゼンに可溶．爆発性を有する．合成用原料，染料や火薬の製造中間体．LD50 268 mg/kg(ラット，経口)．

• 用途

  火薬や爆薬に混ぜて利用される。

• 用途

  危険物第5類の確認試験における熱分析標準品。

• 用途

  爆発物製造時の可塑化剤

• 説明

  2,4-Dinitrotoluene is the most common of the six dinitrotoluene isomers. Dinitrotoluene (DNT) or Dinitro is an explosive with the formula C6H3(CH3)(NO2)2. At room temperature it is a pale yellow to orange crystalline solid. It is a high explosive and one of the precursors for trinitrotoluene (TNT), which is synthesized through three separate nitrations of toluene. The first product is mononitrotoluene, DNT is the second, and TNT is the third and final product. Dinitrotoluene induced sensitization in an employee of a manufacturers of explosives, also sensitized to nitroglycerin.

• 化学的特性

  2,4-Dinitrotoluene (DNT) or dinitro is an organic compound with the formula C7H6N2O4. This pale yellow crystalline solid is well known as a precursor to trinitrotoluene (TNT) but is mainly produced as a precursor to toluene diisocyanate.

• 物理的性質

  Both 2,4-Dinitrotoulene (2,4-DNT) and 2,6-Dinitrotoluene (2,6-DNT) are man-made solids that are pale yellow and have a slight odor. They are two of the six forms of a chemical called Dinitrotoluene (DNT). DNT is made by mixing toluene with nitric acid.

• 使用

  2,4-Dinitrotoluene is used largely, along with the 2,6-isomer, to make toluene diisocyanate. The DNT mixture is hydrogenated to yield the diamine that is reacted with phosgene to form the diisocyanate that is reacted with polyols to make polyurethane foams. DNT is also employed to some extent in manufacturing explosives.

• 定義

  ChEBI: 2,4-dinitrotoluene is a dinitrotoluene in which the methyl group is ortho to one of the nitro groups and para to the other. It is the most common isomer of dinitrotoluene.

• 調製方法

  4-Nitrotoluene is nitrated with mixed acid (containing equimolar HNO3) under controlled conditions and continuous operation to give a 96 % yield of 2,4-dinitrotoluene. In Meissner units, for tighter control of the whole process, cocurrent flow is used in each step to separate mono- and dinitration, but countercurrent flow is used between them to prevent underor overnitration; this is also done in one-step nitration plants. After nitration, if separation of the resulting emulsion is difficult, the introduction of pure product can give surprisingly rapid separation.
  Alternative processes yield mixed isomer products. When toluene is nitrated directly under similar conditions with 2.1 equivalents of nitric acid, the product is a ca. 80 : 20 mixture of 2,4-dinitrotoluene and 2,6-dinitrotoluene [606-20-2]. Nitration of 2-nitrotoluene, which is sometimes present in surplus, gives a ca. 67 : 33 mixture of 2,4- and 2,6-dinitrotoluene. 

• 一般的な説明

  Heated yellow liquid. Solidifies if allowed to cool. Insoluble in water and more dense than water. Toxic by skin absorption, inhalation and ingestion. Easily absorbed through the skin. Produces toxic oxides of nitrogen during combustion. Used to make dyes and other chemicals.

• 空気と水の反応

  Insoluble in water.

• 反応プロフィール

  DINITROTOLUENE is incompatible with strong oxidizing agents, caustics, active metals, tin and zinc . Decomposition occurs at 250°C. Prolonged heating below 250°C causes some decomposition, and the presence of impurities may decrease the decomposition temperatures. Decomposition is self-sustaining at 280°C. Containers may explode in a fire [USCG, 1999]. May react violently in the presence of a base or when heated to the boiling point. Attacks some forms of plastics, rubbers and coatings .

• 健康ハザード

  Ingestion or overexposure to vapors from hot liquid can cause loss of color, nausea, headache, dizziness, drowsiness, collapse. Hot liquid can burn eyes and skin. Prolonged skin contact with solid can give same symptoms as after inhalation or ingestion.

• 安全性プロファイル

  2,4-Dintirotoluene is used as an intermediate in the manufacture of polyurethanes. No information is available on the acute (short-term) effects of 2,4-dinitrotoluene in humans. Chronic (long-term) inhalation exposure to 2,4-dinitrotoluene affects the central nervous system (CNS) and blood in humans. A significant reduction in sperm count and normal sperm morphology was observed in one study of chronically exposed workers, while other studies have not reported this effect. No significant increase in cancer mortality was observed in a study of workers occupationally exposed to 2,4-dinitrotoluene by inhalation. Kidney, liver, and mammary gland tumors were observed in animals orally exposed to 2,4- dinitrotoluene. EPA has not classified 2,4-dinitrotoluene for potential carcinogenicity.

• 環境運命予測

  Biological. When 2,4-dinitrotoluene was statically incubated in the dark at 25 °C with yeast extract and settled domestic wastewater inoculum, significant biodegradation with gradual acclimation was followed by deadaptive process in subsequent subcultures. At a concentration of 5 mg/L, 77, 61, 50, and 27% losses were observed after 7, 14, 21, and 28-d incubation periods, respectively. At a concentration of 10 mg/L, only 50, 49, 44, and 23% were observed after 7, 14, 21, and 28-d incubation periods, respectively (Tabak et al., 1981).
  Photolytic. Low et al. (1991) reported that nitro-containing compounds (e.g., 2,4-dinitrophenol) degrade via UV light in the presence of titanium dioxide yielding ammonium, carbonate, and nitrate ions. By analogy, 2,4-dinitrotoluene should degrade forming identical ions.
  Chemical/Physical. Wet oxidation of 2,4-dinitrotoluene at 320 °C yielded formic and acetic acids (Randall and Knopp, 1980).

• 代謝経路

  The major biliary metabolite of 2,4-dinitrotoluene (2,4- DNT) in the rat is the glucuronide conjugate of 2,4- dinitrobenzyl alcohol and the minor metabolites are 2,4-dinitrobenzyl alcohol, 2,4-dinitrobenzaldehyde, 2- acetylamino-4-nitrotoluene, 4-amino-2-nitro or 2- amino-4-nitrobenzyl alcohol sulfate, 2,4-dinitrobenzoic acid, 2,4-diacetylaminobenzoic acid, and 2-amino-4- nitrobenzoic acid.

• 純化方法

  Crystallise it from Me2CO, isopropanol or MeOH. Dry it in a vacuum over H2SO4. It has also been purified by zone melting. It could be EXPLOSIVE when dry.[Beilstein 5 H339, 5 IV 865, 5 III 759.]

2,4-ジニトロトルエン 上流と下流の製品情報

2,4-ジニトロトルエン スペクトルデータ(¹³CNMR、IR1、IR2、IR3、MS、Raman)

121-14-2, 2,4-ジニトロトルエン キーワード