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Diazapam Structure

Diazapam

Chemical Properties

Melting point 131.5-134.5°C
Boiling point 497.4±45.0 °C(Predicted)
Density  1.2245 (rough estimate)
refractive index  1.6330 (estimate)
Flash point 11 °C
storage temp.  2-8°C
solubility  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.6 mg/mL
form  A neat solid
pka 3.4(at 25℃)
Water Solubility  50mg/L(25 ºC)
BCS Class 1
Stability Stable. Light-sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference 439-14-5(CAS DataBase Reference)
NCI Dictionary of Cancer Terms condition; diazepam; Valium
FDA UNII Q3JTX2Q7TU
NCI Drug Dictionary Zipan
ATC code N05BA01
Proposition 65 List Diazepam
IARC 3 (Vol. Sup 7, 66) 1996
NIST Chemistry Reference 2H-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-(439-14-5)
EPA Substance Registry System Diazepam (439-14-5)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H301+H311-H410
Precautionary statements P273-P280-P301+P310+P330-P302+P352+P312
Hazard Codes  Xn,T,F,Xi
Risk Statements  21/22-39/23/24/25-23/24/25-11-36/37/38
Safety Statements  36/37-45-36-26-16-7
RIDADR  UN 2811 6.1/PG 3
WGK Germany  2
RTECS  DF1575000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2933910000
Hazardous Substances Data 439-14-5(Hazardous Substances Data)
Toxicity LD50 oral in rabbit: 328mg/kg
NFPA 704:
0
2 0

Diazapam Chemical Properties,Usage,Production