Description
This alkaloid, found in Amsonia tabernaemontana, is difficult to obtain crystalline
but the hydrochloride is readily crystallizable and has m.p. 195-6°C; [α]
D -
310° (c 0.134, MeOH).
Chemical Properties
Dark Yellow Low Melting Solid
Occurrence
The seeds of Amsonia elliptica contain this N-oxide at tabersonine.
Uses
(-)-Tabersonine is one of the terpenoid indole alkaloids (TIAs) from Catharanthus roseus. (-)-Tabersonine shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity.
Definition
ChEBI: A monoterpenoid indole alkaloid with cytotoxic activity.
References
lanot, Paourrat, LeMen., Bull. Soc. Chim. Fr., 707 (1954)
Plat et al., Tetrahedron Lett., 271 (1962)
