arsthinol

Originator

Arsthinol,ZYF Pharm Chemical

Uses

Pharmaceutic aid (vehicle, flavored); pharmaceutic F110aid (vehicle, sweetened).

Definition

ChEBI: Arsthinol is a member of acetamides and an anilide.

Manufacturing Process

0.1 mol of 4-hydroxy-3-acetylaminophenyl-arsenoxide is suspended in 50 times its weight of water, and to the suspension 3 mols of sodium carbonate and 11 ml (110 mmols) of 2,3-dimercaptopropanol are added with rapid stirringfor 60 min. The resulting precipitate is filtered off, washed with water and dried in vacuo.
So the N-[2-hydroxy-5-[4-(hydroxymethyl)-1,3,2-dithiarsolan-2-yl]phenyl] acetamide, melting point 163°-166°C is obtained.

Therapeutic Function

Antiprotozoal