Originator
Allobarbital, Fluorochem Ltd.
Uses
Allobarbital is a barbiturate derivative that is primarily used as an anticonvulsant. Allobarbital also shows hypnotic activity and is used to boost the activity of analgesic drugs. Studies show that Allobarbital is an effective promoters of hepatocarcinogenesis.
Allobarbital is a Controlled Substance.
Definition
ChEBI: Allobarbital is a member of barbiturates.
Manufacturing Process
To a mixture of 43 parts barbituric acid, 200 parts of water and 5 parts of
cuprous sulfate in 10 parts of water is added 82 parts of allylbromide. Then at
room temperature is added 27 parts of sodium hydroxide (10% aqueous
solution). 5,5-Diallylbarbituric acid is isolated by filtration. After
recrystallization from water 5,5-diallylbarbituric acid has melting polint 169-
170°C.
Therapeutic Function
Sedative, Hypnotic
