17β-Hydroxyandrost-4-en-3-on-3-phenylpropionat

Bezeichnung:17β-Hydroxyandrost-4-en-3-on-3-phenylpropionat

CAS-Nr1255-49-8

Englisch Name:Testosterone phenylpropionate

CBNumberCB6137357

SummenformelC28H36O3

Molgewicht420.58

MOL-Datei1255-49-8.mol

Synonyma

17β-Hydroxyandrost-4-en-3-on-3-phenylpropionat

17β-Hydroxyandrost-4-en-3-on-3-phenylpropionat physikalisch-chemischer Eigenschaften

Schmelzpunkt	116.5 °C
Siedepunkt	497.74°C (rough estimate)
Dichte	1.0043 (rough estimate)
Brechungsindex	1.5460 (estimate)
Löslichkeit	DMF: 25 mg/mL; DMSO: 5 mg/mL; Ethanol: 15 mg/mL; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
Wasserlöslichkeit	2.25mg/L(25 ºC)
InChIKey	HHSXYDOROIURIP-FEZCWRLCSA-N
SMILES	[C@@]12(CC[C@]3(C)[C@H](CC[C@@]3([H])[C@@]1(CCC1=CC(=O)CC[C@]21C)[H])OC(=O)CCC1C=CC=CC=1)[H] \|&1:0,3,5,8,10,19,r\|
CAS Datenbank	1255-49-8(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	20/21/22-40
S-Sätze:	22-36
WGK Germany	3
RTECS-Nr.	XA3105000

Gefahreninformationscode (GHS)

Testosterone phenylpropionate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Testosterone phenylpropionate (BAN; TPP) (brand name Testolent), or testosterone phenpropionate, also known as testosterone hydrocinnamate, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester – specifically, the C17β phenylpropionate ester of testosterone – which was formerly marketed in Romania. It was first synthesized in 1951 and was first described in the literature by 1953. The medication was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren, as well as of Estandron Prolongatum, Lynandron Prolongatum, and Mixogen. TPP was previously available in Great Britain.
Verwenden
Testosterone 17-Phenylpropionate, is one of the 17b-fatty acid esters of testosterone, that is increasingly misused by athletes in an attempt to improve sports performance, and thus can be used in doping control. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.
Definition
ChEBI: Testosterone phenylpropionate is a steroid ester.
Biologische Funktion
Testosterone phenylpropionate is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester. It was first reported in the scientific literature in 1955 and was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren.
Synthese
In a 100 ml reaction flask, 0.397 g (3 mmol) of cinnamaldehyde was added.0.411g (1.5mmol) Nandrolone, 0.06g (0.3mmol) [Bmim][OAc] catalyst, 10ml 1,4-dioxane, heated to 120 ?? C and then reacted for 2h, after the reaction was completed, cooled to room temperature, added 30 ml of water and 20 ml of ethyl acetate were extracted, and the phases were allowed to stand. The organic phase was concentrated and crystallized to obtain the target product. The yield was 64%.

Testosterone phenylpropionate Upstream-Materialien And Downstream Produkte

17β-Hydroxyandrost-4-en-3-on-3-phenylpropionat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1255-49-8, Testosterone phenylpropionate Verwandte Suche:

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