N4-ACETYL-2'-DEOXYCYTIDINE

Bezeichnung:N4-ACETYL-2'-DEOXYCYTIDINE

CAS-Nr32909-05-0

Englisch Name:N4-ACETYL-2'-DEOXYCYTIDINE

CBNumberCB4470560

SummenformelC11H15N3O5

Molgewicht269.25

MOL-Datei32909-05-0.mol

N4-ACETYL-2'-DEOXYCYTIDINE physikalisch-chemischer Eigenschaften

Schmelzpunkt	150-152 °C
Dichte	1.60±0.1 g/cm3(Predicted)
storage temp.	Store at 0°C
Löslichkeit	DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated), Water (Slightly)
Aggregatzustand	lyophilized
pka	10.28±0.20(Predicted)
Farbe	White to Off-White
Stabilität	Hygroscopic

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26
RIDADR	UN 3264 8 / PGIII
WGK Germany	3

Gefahreninformationscode (GHS)

N4-ACETYL-2'-DEOXYCYTIDINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden
Human ADIPOQ / Adiponectin ELISA Kit has been used in the quantification of leptin and adiponectin from serum and plasma samples.
Definition
ChEBI: N(4)-acetyl-2'-deoxycytidine is 2'-deoxyytidine in which one of the exocyclic amino hydrogens is substituted by an acetyl group. It is a secondary carboxamide and a pyrimidine 2'-deoxyribonucleoside.
Allgemeine Beschreibung
Rat gAcrp30 (amp-1) is a 16.6 kDa protein that corresponds to the C-terminal globular domain of adiponectin (amp-1). gAcrp30/Adipolean is expressed and secreted exclusively by adipose tissue. This protein possesses unique pharmacological properties for regulation of body weight and lipid metabolism. It is a key component in controlling energy homeostasis. Recently, gAcrp30/Adipolean has been shown to inhibit the proliferation of myelomonocytic progenitors. The Recombinant rat gAcrp30/Adipolean is a 16.6 kDa protein consisting of 145 amino acid residues.
Biochem/physiol Actions
In obese mice and humans, adiponectin/gAcrp30 (adipocyte complement-related protein) mRNA expression is reduced, therefore linking this hormone to energy homeostasis. In incubated mouse muscle and cultured cells, gAcrp30 leads to an increase in fatty acid oxidation. This hormone is also linked to anti-atherogenesis, and in apoE-deficient mice, overexpression of gAcrp30 results in significant attenuation of atherosclerosis. Long-term administration of this hormone in mice results in weight loss without reduction in food intake. This hormone is capable of reducing proliferation of MDA-ERα7 cell line. Studies show that ratio of gAcrp30 to leptin and the ERα (estrogen receptor) status of cells are key in determining BRCA (breast cancer) cell growth.

N4-ACETYL-2'-DEOXYCYTIDINE Upstream-Materialien And Downstream Produkte

N4-ACETYL-2'-DEOXYCYTIDINE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

32909-05-0, N4-ACETYL-2'-DEOXYCYTIDINE Verwandte Suche:

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