Tridihexethylchlorid

TRIDIHEXETHYL CHLORIDE (200 MG) Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Tridihexethyl Chloride, is an anticholinergic, antimuscarinic and antispasmodic drug.

• Definition

  ChEBI: Tridihexethyl chloride is an organic chloride salt. It contains a tridihexethyl.

• Trademarks

  Pathilon (Lederle).

• Allgemeine Beschreibung

  Tridihexethyl chloride,3-cyclohexyl-3-hydroxy-3-phenylpropyl)triethylammoniumchloride (Pathilon), is a white, bitter, crystalline powderwith a characteristic odor. The compound is freely soluble inwater and alcohol, with aqueous solutions being nearly neutralin reaction.
  Although this drug, introduced in 1958, has ganglionblockingactivity, its peripheral atropine-like activity predominates;therefore, its therapeutic application has beenbased on the latter activity. It possesses the antispasmodicand the antisecretory activities characteristic of this group,but because of its quaternary character, it is valueless in relievingParkinson syndrome.

• Clinical Use

  tridihexethyl chloride is useful for adjunctive therapy in a wide varietyof GI diseases, such as peptic ulcer, gastric hyperacidity,and hypermotility and spastic conditions, such as spasticcolon, functional diarrhea, pylorospasm, and other relatedconditions. Because its action is predominantly antisecretory,it is more effective in gastric hypersecretion than in hypermotilityand spasm. It is best administered intravenouslyfor the latter conditions.
  The side effects usually found with effective anticholinergictherapy occur with the use of this drug. These are drynessof mouth, mydriasis, and such. As with other anticholinergics,care should be exercised when administering the drug topatients with glaucomatous conditions, cardiac decompensation,and coronary insufficiency. It is contraindicated inpatients with obstruction at the bladder neck, prostatic hypertrophy,stenosing gastric and duodenal ulcers, or pyloric orduodenal obstruction.

Tridihexethylchlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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