CHONDROITIN SULFATE B SODIUM SALT

Bezeichnung:CHONDROITIN SULFATE B SODIUM SALT

CAS-Nr54328-33-5

Englisch Name:CHONDROITIN SULFATE B SODIUM SALT

CBNumberCB3224245

SummenformelNULL

Molgewicht1526.03

MOL-DateiMol file

CHONDROITIN SULFATE B SODIUM SALT physikalisch-chemischer Eigenschaften

Schmelzpunkt	>187°C (dec.)
Brechungsindex	-68 ° (C=1, H2O)
storage temp.	2-8°C
Löslichkeit	H2O: soluble5mg/mL, clear, colorless
Aggregatzustand	lyophilized powder
Farbe	White to Off-White

Sicherheit

S-Sätze:	22-24/25
WGK Germany	3
F	10-21
HS Code	39139000

CHONDROITIN SULFATE B SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Also available: fractionated dermatan sulfates with Av. Mw 25,000 ± 2,500 and 50,000 ± 5,000 and different Anti-Xa and Anti-IIa activities. Please inquire
Verwenden
Chondroitin sulfate B may be used to study its roles as a biomolecule receptor, mediator of cell signaling and cell binding molecule. It may be used to compare its properties to those of chondroitin sulfate A and chondroitin sulfate C. Chondroitin sulfate B is used to study β peptide(1-42) cytotoxicity.
Verwenden
Antithrombotic.
Definition
ChEBI: Dermatan sulfate polyanion is the conjugate base of dermatan sulfate, obtained by deprotonation of carboxy and sulfate groups. It is a monocarboxylic acid anion, an organosulfate oxoanion and a polyanionic polymer. It is a conjugate base of a dermatan sulfate.
Trademarks
Orgaran (Organon).
Allgemeine Beschreibung
Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans. Chondroitin sulfate B (Dermatam sulfate) is a component of proteoglycans such as decorin, biglycan and versican. Chondroitin sulfate B is used to study β peptide (1-42) cytotoxicity.
Biochem/physiol Actions
As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.
läuterung methode
Dermatan sulfate is purified by digestion with papain and hyaluronidase, and fractionation using aqueous EtOH. [Gifonelli & Roden Biochemical Preparations 12 1 1968.]

CHONDROITIN SULFATE B SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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