General Description
A clear or yellow liquid. Bp: 188°C. Toxic by inhalation, by skin absorption, ingestion, and eye contact.
Reactivity Profile
Bis (2-(dimethylamino)ethyl)ether reacts as a base. Reacts exothermically with acids. May form explosive peroxides upon exposure to the air.
Chemical Properties
Brown liquid
Uses
Bis(2-dimethylaminoethyl) ether is an efficient tertiary amine catalyst, which is suitable for the production of almost all foam products, mainly for the production of flexible foam products, especially for high resilience and RIM products. It is characterized by high catalytic activity, smooth foaming, large tolerance to tin, easy to adjust the formulation, and the physical and chemical properties of products produced with it, such as resilience and elongation, are better than other products.
Application
Bis(2-dimethylaminoethyl) Ether (Potassium Clavulanate EP Impurity M) is used in the manufacturing of flexible polyurethane foams.
Preparation
The main methods for the synthesis of Bis(2-dimethylaminoethyl) ether are:
(1) reaction of sodium dimethylaminoethanol and SO3 or chlorosulfonic acid;
(2) Reaction of trimethylamine with dichloroethyl ether or dimethylaminoethoxyethyl ether;
(3) One-step synthesis of dimethylamine and monoethyleneglycol under solid catalyst.
Safety Profile
Poison by skin contact.Moderately toxic by ingestion. Experimental reproductiveeffects. A severe skin and eye irritant.
