6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
- русский язык имя
- английское имя6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole
- CAS №1231930-33-8
- CBNumberCB92500134
- ФормулаC11H12BrFN2
- мольный вес271.13
- EINECS807-019-0
- номер MDLMFCD16660227
- файл Mol1231930-33-8.mol
химическое свойство
| Температура кипения | 353.4±22.0 °C(Predicted) |
| плотность | 1.49 |
| температура хранения | Sealed in dry,Room Temperature |
| пка | 3.48±0.10(Predicted) |
| InChI | InChI=1S/C11H12BrFN2/c1-6(2)15-7(3)14-11-9(13)4-8(12)5-10(11)15/h4-6H,1-3H3 |
| ИнЧИКей | SJQZRZLUEGCXFN-UHFFFAOYSA-N |
| SMILES | C1(C)N(C(C)C)C2=CC(Br)=CC(F)=C2N=1 |
6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole химические свойства, назначение, производство
Использование
6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole is a pharmaceutical intermediate. It can be used in the preparation of Abemaciclib, a kinase inhibitor for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer who have experienced disease progression following endocrine therapy and prior chemotherapy.6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole запасные части и сырье
6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole поставщик
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