5-METHYLCHRYSENE

Химические свойства

Three of the listed PAHs (dibenz[a,h]acridine, dibenz[a,j]acridine, and 7H-dibenzo[c,g]carbazole) contain a nitrogen atom as part of a ring and therefore are classified as heterocyclic PAHs. The PAHs can exist as leaflets, plates, needles, or at room temperature and range in color from colorless to yellow, green or blue. All PAHs are soluble in water and slightly soluble in ethanol, acetone or acid; most are soluble in benzene. Physical and chemical properties of the 15 PAHs are listed in the table below. In addition to the properties listed in the table, benzo[a]pyrene has a specific gravity of 1.351 and a vapor density relative to air of 8.7, and dibenzo[a,h]anthracene has a specific gravity of 1.282 (HSDB 2009).

Использование

5-Methylchrysene is one of the methylated chrysenes (MeChry), as an aryl hydrocarbon receptor (AhR) agonist. Methylated chrysenes (MeChry) are important cigarette smoke constituents and 5-MeChry has been listed as possibly carcinogenic to humans. 5-Methylchrysene is a possible carcinogenic agent.

Общее описание

Purple crystals. Water insoluble.

Реакции воздуха и воды

Dust/air mixture may ignite and explode. Insoluble in water.

Профиль реактивности

Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as 5-METHYLCHRYSENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.

Профиль безопасности

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Канцерогенность

The 15 individual PAHs are reasonably anticipated to be human carcinogens based on sufficient evidence of carcinogenicity from studies in experimental animals.