(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
- русский язык имя
- английское имя(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole
- CAS №681490-95-9
- CBNumberCB83154144
- ФормулаC14H13ClN4O7
- мольный вес384.73
- файл Mol681490-95-9.mol
химическое свойство
| Температура плавления | 122-123 °C(Solv: ethyl acetate (141-78-6); isopropyl ether (108-20-3)) |
| Температура кипения | 638.9±65.0 °C(Predicted) |
| плотность | 1.58±0.1 g/cm3(Predicted) |
| растворимость | Chloroform, DCM |
| форма | Solid |
| пка | 12.81±0.29(Predicted) |
| цвет | Off-White |
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole химические свойства, назначение, производство
Использование
(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-hydroxy-2-methylpropyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole запасные части и сырье
запасной предмет
(R)-2-chloro-1-[2-hydroxy-2-methyl-3-(4-nitrobenzoyloxy)]-propyl-4-nitroimidazole поставщик
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