Oclacitinib maleate
- русский язык имя
- английское имяOclacitinib maleate
- CAS №1640292-55-2
- CBNumberCB83126644
- ФормулаC19H27N5O6S
- мольный вес453.51258
- EINECS-0
- файл Mol1640292-55-2.mol
химическое свойство
| температура хранения | Store at -20°C |
| растворимость | DMSO (Slightly), Methanol (Slightly) |
| форма | Solid |
| цвет | White to Off-White |
| ИнЧИКей | VQIGDTLRBSNOBV-BTJKTKAUSA-N |
| FDA UNII | VON733L42A |
Oclacitinib maleate химические свойства, назначение, производство
Использование
Oclacitinib Maleate is a novel Janus kinase (JAK) inhibitor with activity against cytokines involved in allergy (1,2).Биологическая активность
Oclacitinib was most potent at inhibiting JAK1 (IC50 = 10 nm). Oclacitinib also inhibited the function of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31) at IC50 's ranging from 36 to 249 nM.Oclacitinib maleate поставщик
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China | 4665 | 58 |