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ANTI-MOUSE TENASCIN

  • русский язык имя
  • английское имяANTI-MOUSE TENASCIN
  • CAS №
  • CBNumberCB8146948
  • мольный вес0
  • номер MDLMFCD00164746
  • файл MolMol file
химическое свойство
температура хранения -20°C
Заявления об опасности и безопасности
Коды опасности Xn
Заявления о рисках 21/22
Заявления о безопасности 36/37
WGK Германия 3

ANTI-MOUSE TENASCIN химические свойства, назначение, производство

Использование

Monoclonal Anti-Mouse Tenascin antibody may be used for the localization of tenascin and to study of the role of tenascin in epithelial-mesenchymal interactions using various immunochemical assays including ELISA, immunoblot, dot blot and immunohistology.

Общее описание

Monoclonal Anti-Mouse Tenascin (rat IgG1 isotype) is derived from the MTn-12 hybridoma1 produced by the fusion of rat myeloma cells and splenocytes from a Lou rat immunized with partially purified mouse tenascin. Human tenascin has three subunits of 190, 200 and 220 kDa. Tenascin has been independently discovered in a variety of species and tissue types, often in the basement membrane or intercellular spaces. It has been described under a variety of names: cytotactin, hexabrachion protein, J1, myotendinous antigen (MI) and glioma mesenchymal extracellular matrix (GMEM). The tenascin molecule is a disulfide-linked hexamer, depending on species, the molecular weights of the subunits range from 190 to 320 kDa.

Биохимия/физиол Действия

Tenascin is a high molecular weight, multifunctional, extracellular matrix glycoprotein expressed in association with mesenchymal-epithelial interactions during development and in the neovasculature and stroma of undifferentiated tumors. The expression of tenascin is associated with development and growth, both normal and pathological, whereas the distribution in normal adult tissue is restricted. It was proposed that actively growing, migrating and differentiating epithelial sheets can produce factors that can stimulate tenascin expression in the nearby mesenchyme. Human and chicken tenascin contain an RGD sequence motif which may function in cell adhesion and may be recognized by integrin receptor.

ANTI-MOUSE TENASCIN поставщик

поставщик телефон страна номенклатура продукции благоприятные условия
-- United States 6825 87
-- Switzerland 6913 91