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МОРАЦИЗИН ГИДРОХЛОРИД
- английское имяMORACIZINE HYDROCHLORIDE
- CAS №29560-58-5
- CBNumberCB8115063
- ФормулаC22H26ClN3O4S
- мольный вес463.98
- номер MDLMFCD00329917
- файл Mol29560-58-5.mol
химическое свойство
Температура плавления | 189° (dec) |
форма | Solid |
цвет | Off-white to light brown |
FDA UNII | 71OK3Z1ESP |
Система регистрации веществ EPA | Moricizine hydrochloride (29560-58-5) |
кода HS | 2934302700 |
Токсичность | LD50 in mice, rats (mg/kg): 36, 12 i.v.; in mice (mg/kg): 131 i.p. (Kaverina) |
МОРАЦИЗИН ГИДРОХЛОРИД химические свойства, назначение, производство
Описание
Moricizine hydrochloride is a phenothiazine derivative with antiarrhythmic activity developed by the Soviet Academy of Medical Sciences. It is licensed to Dupont-Sanko in a joint venture. Moricizine hydrochloride is the first drug licensed to a U.S. company by the Soviet Union and was introduced by Dupont in the U.S. in 1990 for specific use in Iife-threatening ventricular arrhythmias. This narrow indication reflects its proarrhythmic potential. The incidence of this adverse reaction, however, is lower than that of other antiarrhythmic agents.Использование
Cardiac depressant (anti-arrhythmic).Определение
ChEBI: A hydrochloride salt obtained from equimola amounts of moricizine and hydrogen chloride.МОРАЦИЗИН ГИДРОХЛОРИД запасные части и сырье
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