Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-
- русский язык имя
- английское имяCholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-
- CAS №28192-77-0
- CBNumberCB78327874
- ФормулаC32H48O7S
- мольный вес576.79
- файл Mol28192-77-0.mol
химическое свойство
| Температура кипения | 674.5±55.0 °C(Predicted) |
| плотность | 1.23±0.1 g/cm3(Predicted) |
| пка | 14.51±0.70(Predicted) |
Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- химические свойства, назначение, производство
Использование
Methyl 3-p-Toluenesulfonate-cholic Acid Ester is an intermediate used in the synthesis of Aramchol (A765150), which is a fatty acid conjugate that exhibits hypocholesterolemic effects and studies have shown that aramchol suppresses the activity of stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.