Dicyclanil

Описание

Dicyclanil is an insect growth regulator belonging to the group of pyrimidinamines.
Dicyclanil is a pyrimidin derivative. Dicyclanil is an insect development inhibitor very specific for the prevention of blowfly strike in sheep. It does not control any other external parasites of sheep. It is used mainly as a spray-on. It is not used in other livestock, horses or pets.

Использование

Dicyclanil is a veterinary medication for the protection against early season myiasis.

прикладной

Dicyclanil may be used as an analytical reference standard for the quantification of the analyte in biological samples, bovine, porcine and chicken muscle using various chromatography techniques.

Фармакокине?тика

Dicyclanil has a long lasting action which interferes with moulting and pupation in dipteran species. However, the precise mode of action of this compound on ectoparasites is not known.
A variety of in vitro and in vivo pharmacodymanic tests were performed with dicyclanil in rats, mice and guinea pigs. In vitro, dicyclanil was devoid of significant effects on the neuromuscular junction at concentrations below 3 mM. Slight antagonistic effects on smooth muscle were reported at concentration levels above 0.1 mM. Dicyclanil caused a statistically significant increase in heart rate, tidal volume and minute volume at a dose level of 100 mg/kg bw in studies on the cardiovascular and respiratory systems in the rat. In various in vivo studies, dicyclanil was devoid of significant effects on behavior at a dose level of 1 mg/kg bw in mice.