СНС 80

Описание

SNC 80 is a selective nonpeptide agonist of the δ-opioid receptor (K_i = 0.18 nM, IC₅₀ = 2.73 nM) that is over 2,000-fold less effective at the μ-opioid receptor. It effectively activates μ/δ receptor heteromers (EC₅₀ = 52.8 nM) but not κ/δ or μ/κ heteromers. SNC 80 has antinociceptive as well as pro-convulsant effects in vivo.

Химические свойства

Crystalline Solid

Использование

A highly selective and potent non-peptide -agonist, 2000-fold selective over u-receptors

Биологическая активность

A highly selective and potent non-peptide δ -opioid agonist, 2000-fold selective over μ -opioid receptors.